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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKP1 All Species: 13.94
Human Site: S518 Identified Species: 34.07
UniProt: Q13835 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13835 NP_000290.2 747 82861 S518 T G C F S N K S D K M M N N N
Chimpanzee Pan troglodytes XP_514090 747 82870 S518 T G C F S N K S D K M M N N N
Rhesus Macaque Macaca mulatta XP_001091487 984 109205 T588 K K K K K K R T P Q E D Q W D
Dog Lupus familis XP_848640 759 83859 S530 T G C F S N K S D K M M N N N
Cat Felis silvestris
Mouse Mus musculus P97350 728 80878 N504 R G D K M M N N N Y D C P L P
Rat Rattus norvegicus NP_001100651 605 67199 C388 I I P F S G W C D G N S N M S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510271 496 54506 L279 N N N C D L P L P E E D S K P
Chicken Gallus gallus XP_419240 723 80049 S506 T G C F N S R S G K M E N D E
Frog Xenopus laevis Q8AXM9 859 94542 G552 S C F G V R R G K G K K A S E
Zebra Danio Brachydanio rerio XP_001338299 736 80304 Q504 P I I C F R L Q S Q K L K Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 22 92 N.A. 92.3 77.5 N.A. 55 66.5 22.7 33.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 38.2 94.7 N.A. 95 79.1 N.A. 59.7 79.9 40.1 54 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 6.6 26.6 N.A. 0 53.3 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 20 33.3 N.A. 13.3 80 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 10 40 20 0 0 0 10 0 0 0 10 0 0 0 % C
% Asp: 0 0 10 0 10 0 0 0 40 0 10 20 0 10 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 20 10 0 0 20 % E
% Phe: 0 0 10 50 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 50 0 10 0 10 0 10 10 20 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 20 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 10 10 20 10 10 30 0 10 40 20 10 10 10 0 % K
% Leu: 0 0 0 0 0 10 10 10 0 0 0 10 0 10 0 % L
% Met: 0 0 0 0 10 10 0 0 0 0 40 30 0 10 0 % M
% Asn: 10 10 10 0 10 30 10 10 10 0 10 0 50 30 30 % N
% Pro: 10 0 10 0 0 0 10 0 20 0 0 0 10 0 20 % P
% Gln: 0 0 0 0 0 0 0 10 0 20 0 0 10 10 0 % Q
% Arg: 10 0 0 0 0 20 30 0 0 0 0 0 0 0 10 % R
% Ser: 10 0 0 0 40 10 0 40 10 0 0 10 10 10 10 % S
% Thr: 40 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _